The most common cause of viral resistance, reduced effectiveness, and therapeutic failure with antiretroviral therapy (ART) is nonadherence to the recommended drug regimen. Full adherence to most medications requires that patients take 95% of their dose at the recommended times. Yet studies find various rates of non-adherence or sub-optimal use ranging from 17% to as high as 95%. In HIV treatment, adherence rates as low as 50% contribute to viral resistance and reduce the protective effects … [Read more...]